See also: Eric Clapton
| Game | Song | Year | Album |
|---|---|---|---|
| Guitar Hero | Crossroads (cover) | 2005 | Wheels of Fire |
| Guitar Hero III: Legends of Rock | Sunshine of Your Love (cover) | 2007 | Disraeli Gears |
| Rock Revolution | White Room (cover) | 2008 | Wheels of Fire |
| Rocksmith | Sunshine of Your Love | 2011 | Disraeli Gears |
| Mafia III | White Room | 2016 | Wheels of Fire |
| Beatstar | Sunshine of Your Love | 2023 | Disraeli Gears |