| Game | Song | Year |
|---|---|---|
| Street Hoops | Who We Be | 2002 |
| Test Drive: Overdrive | We Right Here | 2002 |
| Def Jam Vendetta | Intro | 2003 |
| Def Jam Vendetta | Party Up | 2003 |
| Def Jam Vendetta | X Gon' Give It to Ya | 2003 |
| Tiger Woods PGA Tour 04 | Party Up | 2003 |
| Get On Da Mic | Ruff Ryders' Anthem | 2004 |
| Get On Da Mic | X Gon' Give It to Ya | 2004 |
| Madden NFL 2005 | Yung Wun ft. DMX, David Banner, and Lil Flip- Tear It Up | 2004 |
| NFL Street 2 | Yung Wun ft. DMX, David Banner, and Lil Flip- Tear It Up | 2004 |
| Grand Theft Auto: Liberty City Stories | Ruff Ryders' Anthem (Remix) | 2005 |
| Grand Theft Auto: Liberty City Stories | Get At Me Dog | 2005 |
| NARC | The Professional | 2005 |
| True Crime: New York City | Where The Hood At | 2005 |
| Def Jam Rapstar | Party Up | 2010 |
| Def Jam Rapstar | Ruff Ryders' Anthem | 2010 |
| EA Sports UFC | Ain't No Sunshine | 2014 |
| EA Sports UFC 2 | Ain't No Sunshine | 2016 |
| EA Sports UFC 2 | Intro | 2016 |
| EA Sports UFC 2 | N.A.S.A. ft. DMX & Priyanka Chopra- Meltdown | 2016 |
| Forza Horizon 3 | X Gon' Give It to Ya | 2016 |
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