| Game | Song | Year | Album |
|---|---|---|---|
| Power Gig: Rise of the SixString | Lay Down Sally | 2010 | Slowhand |
| Power Gig: Rise of the SixString | Layla | 2010 | Layla and Other Assorted Love Songs |
| Power Gig: Rise of the SixString | Let It Grow | 2010 | 461 Ocean Boulevard |
| Rocksmith | Run Back to Your Side | 2011 | Clapton |
| Grand Theft Auto V (beta) | Cocaine | 2013 | Slowhand |
| Rocksmith+ | Tears in Heaven (cover) | 2024 | Rush: Music from the Motion Picture Soundtrack |
| Rocksmith+ | Wonderful Tonight (cover) | 2024 | Slowhand |
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Eric Clapton
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