Megadeth is an American thrash metal band formed in Los Angeles in 1983 by vocalist/guitarist Dave Mustaine.
| Game | Song | Year | Album |
|---|---|---|---|
| Ultimate Fighting Championship | Crush 'Em | 2000 | Risk |
| Heavy Metal: Geomatrix | Moto Psycho | 2001 | The World Needs a Hero |
| Grand Theft Auto: Vice City | Peace Sells | 2002 | Peace Sells... but Who's Buying? |
| True Crime: Streets of LA | Peace Sells | 2003 | Peace Sells... but Who's Buying? |
| Symphony of Destruction | Countdown to Extinction | ||
| Freestyle MetalX | Crush 'Em | 2003 | Risk |
| Peace Sells | Peace Sells... but Who's Buying? | ||
| Devil's Island | Peace Sells... but Who's Buying? | ||
| Guitar Hero | Symphony of Destruction | 2005 | Countdown to Extinction |
| WWE SmackDown! vs. Raw 2006 | Symphony of Destruction (Remix) | 2005 | Countdown to Extinction |
| FlatOut 2 | Symphony of Destruction | 2006 | Countdown to Extinction |
| Guitar Hero II | Hangar 18 | 2006 | Rust in Peace |
| NFL Street 3 | Symphony of Destruction (Fear Factory Remix) | 2006 | Countdown to Extinction |
| Full Auto 2: Battlelines | Symphony of Destruction (The Gristle Mix) | 2006 | Single |
| Rock Band (DLC) | Sleepwalker | 2008 | United Abominations |
| Rock Band 2 | Peace Sells | 2008 | Peace Sells... but Who's Buying? |
| Rock Band 2 (DLC) | Wake Up Dead | 2008 | Peace Sells... but Who's Buying? |
| The Conjuring | Peace Sells... but Who's Buying? | ||
| Devil's Island | Peace Sells... but Who's Buying? | ||
| Good Mourning/Black Friday | Peace Sells... but Who's Buying? | ||
| Bad Omen | Peace Sells... but Who's Buying? | ||
| I Ain't Superstitious | Peace Sells... but Who's Buying? | ||
| My Last Words | Peace Sells... but Who's Buying? | ||
| Rock Revolution | Holy Wars... The Punishment Due | 2008 | Rust in Peace |
| MotorStorm: Pacific Rift | Sleepwalker | 2008 | United Abominations |
| Guitar Hero 5 | Sweating Bullets | 2009 | Countdown to Extinction |
| NHL 10 | Peace Sells | 2009 | Peace Sells... but Who's Buying? |
| Brütal Legend | High Speed Dirt | 2009 | Countdown to Extinction |
| Tornado of Souls | Rust in Peace | ||
| Rock Band 2 (DLC) | Holy Wars... The Punishment Due | 2010 | Rust in Peace |
| Hangar 18 | |||
| Take No Prisoners | |||
| Five Magics | |||
| Poison Was the Cure | |||
| Lucretia | |||
| Tornado of Souls | |||
| Dawn Patrol | |||
| Rust in Peace... Polaris | |||
| Guitar Hero 5 (DLC) | Hangar 18 | 2010 | Rust in Peace |
| Peace Sells | Peace Sells... but Who's Buying? | ||
| Symphony of Destruction | Countdown to Extinction | ||
| NHL 11 | Dialectic Chaos | 2010 | Endgame |
| Guitar Hero: Warriors of Rock | Holy Wars... The Punishment Due | 2010 | Rust in Peace |
| Sudden Death | Th1rt3en | ||
| This Day We Fight! | Endgame | ||
| Rock Band Reloaded | Peace Sells | 2010 | Peace Sells... but Who's Buying? |
| Power Gig: Rise of the SixString (Beta DLC) | Tornado of Souls | 2010 | Rust in Peace |
| Operation Flashpoint: Red River | Symphony of Destruction (Remix) | 2011 | Countdown to Extinction |
| NeverDead | Never Dead | 2012 | Th1rt3en |
| Rock Band 3 (DLC) | Symphony of Destruction | 2012 | Countdown to Extinction |
| À Tout Le Monde | Youthanasia | ||
| Public Enemy No. 1 | Th1rt3en | ||
| BandFuse: Rock Legends | Hangar 18 | 2013 | Rust in Peace |
| Guitar Hero Live | Hangar 18 | 2015 | Rust in Peace |
| Rock Band 4 (DLC) | Dystopia | 2016 | Dystopia |
| Watch Dogs 2 | Fatal Illusion | 2016 | Dystopia |
| Rock Band 4 (DLC) | Trust | 2017 | Cryptic Writings |
| Rock Band VR | Hangar 18 | 2017 | Rust in Peace |
| Rock Band 4 (DLC) | Peace Sells | 2019 | Peace Sells... but Who's Buying? |
| Rock Band 4 (DLC) | Fatal Illusion | 2021 | Dystopia |
| Beatstar | Tornado of Souls | 2022 | Rust in Peace |
| Beatstar | Symphony of Destruction | 2023 | Countdown to Extinction |
| Rocksmith+ | Hangar 18 (cover) | 2023 | Rust in Peace |
| Tap Tap Reloaded | Tornado of Souls | 2023 | Rust in Peace |
| This Day We Fight! | Endgame | ||
| Sleepwalker | United Abominations | ||
| Peace Sells | Peace Sells... but Who's Buying? | ||
| Rocksmith+ | Tornado of Souls (cover) | 2024 | Rust in Peace |