Groups: Wu-Tang Clan, Method Man & Redman
| Game | Song | Year | Album |
|---|---|---|---|
| Wu-Tang: Shaolin Style | U-God ft. Inspectah Deck, Letha Face & Method Man - Rumble | 1999 | Wu-Tang Collective |
| Def Jam Vendetta | Bring the Pain | 2003 | Tical |
| Def Jam Vendetta | Uh Huh! | 2003 | Tical 0: The Prequel |
| Def Jam: Fight for NY | What's Happenin' (feat. Busta Rhymes) | 2004 | Tical 0: The Prequel |
| Freestyle Street Soccer | Perfect World | 2004 | Tical 2000: Judgement Day |
| Grand Theft Auto: Liberty City Stories | All I Need (feat. Mary J. Blige | 2005 | Tical |
| Grand Theft Auto: Liberty City Stories | Redman ft. Method Man - Do What Ya Feel | 2005 | Muddy Waters |
| Saints Row | Mathematics feat. Method Man & P.I. - John 3:16 | 2006 | The Problem |
| Fight Night Round 4 | N.A.S.A ft. Method Man, E-40, DJ Swamp - N.A.S.A. Music | 2009 | The Spirit of Apollo |
| Def Jam Rapstar | I'll Be There for You / You're All I Need to Get By (feat. Mary J. Blige) | 2010 | Tical |
| Def Jam Rapstar (DLC) | Raekwon feat. Method Man, Ghostface Killah and Cappadonna - Ice Cream | 2010 | Only Built 4 Cuban Linx... |
| EA Sports MMA | Bring the Pain | 2010 | Tical |
| Madden NFL 16 | GOH vs. Sugarstarr feat. Redman & Method Man - I Used to Be | 2015 | Single |
| EA Sports UFC 5 | PROF - Subpar feat. Method Man | 2023 | Horse |