Slayer is an American thrash metal band from Huntington Park, California, formed in 1981 by guitarists Kerry King and Jeff Hanneman, drummer Dave Lombardo and bassist/vocalist Tom Araya. Slayer released twelve studio albums, three live albums, a box set, six music videos, two extended plays and a cover album. Slayer announced in 2018 that it would embark on a farewell tour, which took place from May 2018 to November 2019, after which they disbanded. However, Slayer has reunited to perform a handful of reunion shows since 2024.
| Game | Song | Year | Album |
|---|---|---|---|
| Grand Theft Auto: Vice City | Raining Blood | 2002 | Reign in Blood |
| SSX on Tour | DJ Spooky & Dave Lombardo - B-Side Wins Again | 2005 | Drums of Death |
| Need for Speed: Most Wanted | DJ Spooky & Dave Lombardo feat. Chuck D - B-Side Wins Again | 2005 | Drums of Death |
| Tony Hawk's Project 8 | Angel of Death | 2006 | Reign in Blood |
| Skate | Raining Blood | 2007 | Reign in Blood |
| Guitar Hero III: Legends of Rock | Raining Blood | 2007 | Reign in Blood |
| Guitar Hero: Metallica | War Ensemble | 2009 | Seasons in the Abyss |
| Guitar Hero Smash Hits | Raining Blood | 2009 | Reign in Blood |
| Brütal Legend | Metal Storm/Face the Slayer | 2009 | Show No Mercy |
| Rock Band 2 (DLC) | Black Magic | 2009 | Show No Mercy |
| Guitar Hero: Warriors of Rock | Chemical Warfare | 2010 | Haunting the Chapel |
| Homefront | As I Lay Dying - War Ensemble (Slayer cover) | 2011 | Homefront - Songs for the Resistance |
| Rock Band 3 (DLC) | Raining Blood | 2012 | Reign in Blood |
| South of Heaven | South of Heaven | ||
| Seasons in the Abyss | Seasons in the Abyss | ||
| Rocksmith 2014 | War Ensemble | 2013 | Seasons in the Abyss |
| Rock Band 4 (DLC) | Angel of Death | 2019 | Reign in Blood |
| Saints Row (2022) | Repentless | 2022 | Repentless |
| Rocksmith+ | Necrophiliac | 2022 | Hell Awaits |
| Tap Tap Reloaded | Raining Blood | 2023 | Reign in Blood |
| Angel of Death | Reign in Blood | ||
| Rocksmith+ | Raining Blood | 2024 | Reign in Blood |