The Isley Brothers are an American soul group originally from Cincinnati, Ohio, that began as a vocal trio consisting of the brothers O'Kelly Isley Jr., Rudolph Isley and Ronald Isley in the 1950s. With a career spanning over seven decades, the group has enjoyed one of the "longest, most influential, and most diverse careers in the pantheon of popular music".
| Game | Song | Year |
|---|---|---|
| Karaoke Revolution | This Old Heart of Mine (Is Weak for You) (cover) | 2003 |
| Grand Theft Auto: San Andreas | Between the Sheets | 2004 |
| Dancing Stage MAX | Shout | 2005 |
| Dance Dance Revolution SuperNOVA | Shout | 2006 |
| Grand Theft Auto IV | Footsteps In The Dark | 2008 |
| Karaoke Revolution Presents: American Idol Encore (DLC) | This Old Heart of Mine (Is Weak for You) (cover) | 2008 |
| SingStar Motown | This Old Heart of Mine (Is Weak for You) | 2009 |
| Madden NFL 12 | Shout (Buffalo Bills Version) | 2011 |
| Rock Band 4 (DLC) | Shout | 2015 |